Presence of carbepenemase-producing Enterobacteriaceae in the River Lambro basin, Italy: might sediment represent an important resistance reservoir?

https://doi.org/10.4081/jlimnol.2021.2029

Authors

  • Sara Giordana Rimoldi Laboratorio di Microbiologia Clinica, Virologia e Diagnostica delle Bioemergenze, ASST Fatebenefratelli Sacco, Milan , Italy.
  • Francesca Romeri Laboratorio di Microbiologia Clinica, Virologia e Diagnostica delle Bioemergenze, ASST Fatebenefratelli Sacco, Milan , Italy.
  • Anna Gigantiello Laboratorio di Microbiologia Clinica, Virologia e Diagnostica delle Bioemergenze, ASST Fatebenefratelli Sacco, Milan , Italy.
  • Cristina Pagani Laboratorio di Microbiologia Clinica, Virologia e Diagnostica delle Bioemergenze, ASST Fatebenefratelli Sacco, Milan , Italy.
  • Luigi Viganò Water Research Institute-National Research Council (IRSA-CNR), Brugherio (MB), Italy.
  • Annunziata Calvagna Laboratorio di Microbiologia Clinica, Virologia e Diagnostica delle Bioemergenze, ASST Fatebenefratelli Sacco, Milan , Italy.
  • Alessandro Tamoni Laboratorio di Microbiologia Clinica, Virologia e Diagnostica delle Bioemergenze, ASST Fatebenefratelli Sacco, Milan , Italy.
  • Mafalda Maresca Laboratorio di Microbiologia Clinica, Virologia e Diagnostica delle Bioemergenze, ASST Fatebenefratelli Sacco, Milan , Italy.
  • Maria Rita Gismondo Laboratorio di Microbiologia Clinica, Virologia e Diagnostica delle Bioemergenze, ASST Fatebenefratelli Sacco, Milan , Italy.
  • Fabrizio Stefani | stefani@irsa.cnr.it Water Research Institute-National Research Council (IRSA-CNR), Brugherio (MB), Italy. https://orcid.org/0000-0001-5200-0529

Abstract

In the last years, the rapid spread in anthropized ecosystems of pathogens which are resistant to carbapenem antibiotics has raised great concern. In this study, KPC-producing Klebsiella pneumoniae was found in the River Lambro in June 2019, whereas KPC-producing Klebsiella oxytoca and Citrobacter braakii were identified in untreated wastewaters. Susceptibility profiles indicated resistance to imipenem, ertapenem and meropenem. Different carbapenamase genes (blaKPC, blaNDM, blaVIM, blaOXA-48) were also found in the River Lambro, although not associated to living bacteria. The presence of a wide set of carbapenemase genes and resistant pathogens show that river sediments could act as a reservoir of antibiotic resistance potentially threatening human health.

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References

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River Lambro
Published
2021-07-20
Info
Issue
Section
80 Years of the Journal of Limnology
Keywords:
River Lambro, Klebsiella, carbapenemase, blakpc, Enterobacteriaceae
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How to Cite
1.
Rimoldi SG, Romeri F, Gigantiello A, Pagani C, Viganò L, Calvagna A, Tamoni A, Maresca M, Gismondo MR, Stefani F. Presence of carbepenemase-producing Enterobacteriaceae in the River Lambro basin, Italy: might sediment represent an important resistance reservoir?. J Limnol [Internet]. 2021 Jul. 20 [cited 2021 Jul. 28];. Available from: https://jlimnol.it/index.php/jlimnol/article/view/2029

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